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I take baclofen for extreme pain in shoulder and arm due to compressed neck vertebrae. I had tried Flexeril and Robaxin and received no relief. When I first began taking this I couldn't sleep, had a headache and as I read a review by another person - fell asleep mid sentence. My boss said I was hard to get to understand things but very agreeable. All are getting better. I have very vivid dreams now and wake about every 3 or 4 hours to go to the bathroom - that I was doing prior to the drug. What I call "pee pee pads" are very important but I used them prior to taking Baclofen. Overall, this medicine seems to help most of the time. I take it just before leaving for work just in case I might have trouble driving. Works well.

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Baclofen is one of the medications most commonly used to treat spasticity.

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Baclofen acts on the central nervous system to relieve spasms, cramping, and tightness of muscles caused by spasticity in multiple sclerosis.

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The pump would then distribute a controlled dosage directly into her spinal fluid, hopefully controlling her spasms without many of the side effects of oral baclofen (drowsiness, dry mouth).

The management of ITB Therapy SM has a sequence of phases.

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One of the women (Patient 2), who had initially required a wheelchair, was able to walk with assistance after she received the 75-μg dose of baclofen, and another woman (Patient 5), whose dystonia predominantly involved the extensor muscles, had a general feeling of relaxation, without any decrease in her dystonia.

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Intrathecal baclofen was superior to placebo on both principal outcome measures employed: change from baseline in the Ashworth rating of spasticity and the frequency of spasms.

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Further study is warranted in all these areas, with a focus on determining the most beneficial timing and dosage of each intervention, the varying effects on the different aspects of the spasticity syndrome after SCI, and the varying effects in persons with different levels and completeness of SCI.

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